When you need to start Windows 10 using Safe Mode
One of the ways to enter to safe mode in Windows 10 is through the System Configuration menu.
While Windows running go to Run command by pressing the combination keys Windows+R
• Type msconfig then click Ok or hit Enter
• Go to Boot tab.
• Under Boot options, give a tick at Safe boot.
• Click Ok.
• The warning will appear asking the computer will restart, then choose Restart.
After boot, Windows will run in the Safe Mode.